Full Course Description

Pharmacology of Infectious Diseases & Immunizations for Advanced Practice Clinicians

Program Information

Objectives

Analyze the major classes of antibiotics and their pharmacokinetic characteristics.
Apply current evidenced-based approaches to select appropriate treatment regimens for common infections encountered in clinical practice.
Prescribe antimicrobials based on empiric dosing recommendations.
Plan goals of therapy and parameters for monitoring therapeutic response to antimicrobials.
Recommend specific antimicrobial therapeutic drug monitoring to maximize efficacy and minimize toxicities (e.g., vancomycin and aminoglycosides).
Develop preventative strategies to limit antimicrobial resistance.
Design patient and caregiver education on the proper use of antimicrobials.

Outline

Antimicrobials

Drug classes
Pharmacokinetic Properties
- Concentration-dependent killing
- Time-dependent killing
- Post-antibiotic effect
Common interactions with other drugs

Antibacterial Allergies - Sulfa and Penicillin

Define true allergy
Sulfonamide antibiotics vs non-antibiotics
Penicillin - Cephalosporin cross-sensitivity

Bacteria

Differentiation
Normal flora
Common pathogens

Antibacterial Resistance - Contributing Factors

Trends
Mechanisms of resistance
Contributing factors

Methicillin-Resistant Staphylococcus Aureus - Community versus Hospital Acquired

Differentiating between CA- and HA-MRSA
Current clinical practice guidelines
Pharmacologic management

Enterobacteriaceae Resistance

Extended Spectrum Beta-Lactamase (ESBL)
- What are ESBLs
- Pharmacologic management
Carbapenem-Resistant Enterobacteriaceae (CRE)
- What are CREs
- Pharmacologic management

Urinary Tract Infections

Bacterial Etiology, Signs and Symptoms and Diagnosis
Cystitis and pyelonephritis
Complicated and uncomplicated
UTIs in pregnancy
Treatment (IDSA Guideline Treatment Algorithm)
- Acute
- Recurrent and relapse

Clostridium Difficile Infection

Risk factors
Pharmacology management
Fecal Transplantation
Probiotics literature review

Community–Acquired Pneumonia

Bacterial etiology
Diagnosis
Typical vs. atypical
Treatment (IDSA/ATS Guidelines) and monitoring
- Outpatient vs. inpatient
- Empiric treatment

Healthcare–Associated Pneumonia

Bacterial etiology
Treatment (IDSA/ATS Guidelines)

Upper Respiratory Tract Infections

Sinusitis and pharyngitis
- Etiology (Viral vs. Bacterial)
- Treatment

Skin and Soft Tissue Infections

Cellulitis
Bacterial etiology
- Strep. vs. Staph. vs. MRSA
- Signs & symptoms
- Treatment (IDSA Guidelines)

Influenza

Clinical features
Diagnosis
Pharmacology management

Immunizations (Adult)

Types of Vaccines
General recommendations
Contraindications & precautions

Target Audience

Nurses
Advanced Practice Nurses
Clinical Nurse Specialists
Pharmacists
Nurse Practitioners
Physician Assistants

Copyright : 07/13/2020

Infection Control Challenges: Real Risks for Patients and Staff

Program Information

Objectives

Plan strategies to reduce and eliminate catheter-associated urinary tract infections, surgical site infections, ventilator associated and non-ventilator-associated pneumonias and central-line-associated bloodstream infections.
Assess best practices for treatment and control of multi-drug resistant microorganisms, including MRSA, Clostridium difficile, VRE, ESBL and CRE.
Evaluate the newest vaccine recommendations for healthcare workers and children.
Distinguish between mosquito-borne illnesses of Dengue, Chikungunya, and Zika, which may be a threat to the United States.
Assess the latest treatments available for HIV/AIDS, as well as pre-exposure prophylaxis.
Determine the medications available that "cure" Hepatitis C.
Evaluate the current recommendations to control and treat tuberculosis.

Outline

A Summary of Current Recommendations From the CDC, SHEA, IDSA, APIC and the Joint Commission

Health-Care Associated Infections: Strategies to Control-Reduce-Eliminate

Catheter-Associated Urinary Tract Infections
Surgical Site Infections
Ventilator-Associated Pneumonias
Non-ventilator Associated Infections (overlooked HAI)
Central-Line Associated Bloodstream Infections

The Latest Multi-Drug Resistant Microorganism Guidelines

Carbapenem-resistant enterobacteriaceae
Clostridium difficile
Methicillin-resistant staphylococcus aureus
Vancomycin resistant enterococcus
Acinetobacter baumannii

Influenza

Avian vs. swine vs. seasonal influenza
H1N1 pandemic results
When to treat? When not to treat?
Treatment with anti-virals and antibiotics
New vaccines for flu

Vaccination Recommendations for Healthcare Personnel

Zoster/shingles
Pneumoccocal
MMR, Tdap, etc.

Emerging Infectious Diseases (Zoonotic)

Ebola: What we learned
Mosquito-borne ("Zika", Dengue, Chickungunya, West Nile)
Tick-borne (Lyme and Babesia)
Cryptosporidiosis

Bloodborne Pathogens

Hepatitis B
- Vaccination protocol for healthcare personnel
- Staff follow-up after significant exposures
- Treatments for persons chronically infected
- Outbreaks in healthcare
Hepatitis C
- Treatment "cures" in 12-24 weeks
- Outbreaks in healthcare-dialysis settings
HIV/AIDS
- New one pill daily treatment
- Healthcare exposure and appropriate prophylaxis

Tuberculosis

Today's best approaches to treatment
Skin testing vs. blood test for exposure
Follow-up guidelines for healthcare workers conversion testing

Target Audience

Nurses
Infection Preventionists
Nurse Practitioners
Clinical Nurse Specialists
Nurse Educators

Pharmacological Management of Infectious Diseases

Choosing an antibacterial agent can be challenging given the emerging trends in bacterial resistance. In this session, Dr. Langlois discusses pharmacokinetic properties and new treatment guidelines for conditions commonly encountered in critical care including:

Urinary Tract Infections
Skin & Soft Tissue Infections
Multiple Drug-Resistant Organisms

Outline

Bacterial Basics
- Cell Envelope
- Fungal Infections
- UTI
- Pevlic Inflammatory Disease
  - PID Therapy
- Cellulitis
  - Bacterial Causes
  - Therapy for Cellulitis
- Diabetic Foot Infections
  - Diagnosis and Treatment of Osteomyelitis in Diabetic Ulcer
Strategies to Improve Patient Adherence
- IMS Model
- Prescribing Practices
- Antibiotic Resistance
- Antimicrobial Resistance

Program Information

Target Audience

Nurses, Nurse Practitioners, Clinical Nurse Specialists, Other

Objectives

Catalogue major classes of antibiotics and their pharmacokinetic characteristics.
Choose appropriate pharmacologic and nonpharmacologic regimens for the prevention and treatment in various patient populations.