Full Course Description

Pharmacology of Infectious Diseases & Immunizations for Advanced Practice

Purchase this recording and learn proper prescribing, patient education and monitoring procedures for a variety of drug regimens used to treat common acute and chronic infectious diseases. Choosing an antibacterial agent can be challenging, given the plethora of drugs available on the market and the emerging trend in bacterial resistance.

You will learn the pharmacology of different classes of antimicrobials used to treat infectious disease states encountered in clinical practice. Discover the spectrums of activity, pharmacokinetic characteristics and parameters for monitoring therapeutic outcomes. Emphasis is placed on the new antimicrobials and advances in evidence-based treatment guidelines. You will finish this program better prepared to design appropriate and cost-effective drug regimens for improved therapeutic outcomes.

Program Information

Objectives

  1. Analyze the major classes of antibiotics and their pharmacokinetic characteristics.
  2. Apply current evidenced-based approaches to select appropriate treatment regimens for common infections encountered in clinical practice.
  3. Prescribe antimicrobials based on empiric dosing recommendations.
  4. Plan goals of therapy and parameters for monitoring therapeutic response to antimicrobials.
  5. Recommend specific antimicrobial therapeutic drug monitoring to maximize efficacy and minimize toxicities (e.g., vancomycin and aminoglycosides).
  6. Develop preventative strategies to limit antimicrobial resistance.
  7. Design patient and caregiver education on the proper use of antimicrobials.

Outline

Antimicrobials

  • Drug classes
  • Pharmacokinetic Properties
    • Concentration-dependent killing
    • Time-dependent killing
    • Post-antibiotic effect
  • Common interactions with other drugs

Antibacterial Allergies - Sulfa and Penicillin

  • Define true allergy
  • Sulfonamide antibiotics vs non-antibiotics
  • Penicillin - Cephalosporin cross-sensitivity

Bacteria

  • Differentiation
  • Normal flora
  • Common pathogens

Antibacterial Resistance - Contributing Factors

  • Trends
  • Mechanisms of resistance
  • Contributing factors

Methicillin-Resistant Staphylococcus Aureus - Community versus Hospital Acquired

  • Differentiating between CA- and HA-MRSA
  • Current clinical practice guidelines
  • Pharmacologic management

Enterobacteriaceae Resistance

  • Extended Spectrum Beta-Lactamase (ESBL)
    • What are ESBLs
    • Pharmacologic management
  • Carbapenem-Resistant Enterobacteriaceae (CRE)
    • What are CREs
    • Pharmacologic management

Urinary Tract Infections

  • Bacterial Etiology, Signs and Symptoms and Diagnosis
  • Cystitis and pyelonephritis
  • Complicated and uncomplicated
  • UTIs in pregnancy
  • Treatment (IDSA Guideline Treatment Algorithm)
    • Acute
    • Recurrent and relapse

Clostridium Difficile Infection

  • Risk factors
  • Pharmacology management
  • Fecal Transplantation
  • Probiotics literature review

Community–Acquired Pneumonia

  • Bacterial etiology
  • Diagnosis
  • Typical vs. atypical
  • Treatment (IDSA/ATS Guidelines) and monitoring
    • Outpatient vs. inpatient
    • Empiric treatment

Healthcare–Associated Pneumonia

  • Bacterial etiology
  • Treatment (IDSA/ATS Guidelines)

Upper Respiratory Tract Infections

  • Sinusitis and pharyngitis
    • Etiology (Viral vs. Bacterial)
    • Treatment

Skin and Soft Tissue Infections

  • Cellulitis
  • Bacterial etiology
    • Strep. vs. Staph. vs. MRSA
    • Signs & symptoms
    • Treatment (IDSA Guidelines)

Influenza

  • Clinical features
  • Diagnosis
  • Pharmacology management

Immunizations (Adult)

  • Types of Vaccines
  • General recommendations
  • Contraindications & precautions

Target Audience

  • Nurses
  • Advanced Practice Nurses
  • Clinical Nurse Specialists
  • Pharmacists
  • Nurse Practitioners
  • Physician Assistants

Copyright : 07/13/2020

Infection Control Challenges: Real Risks for Patients and Staff

Barry Inman, BA-BS, CIC, will share practical solutions to a variety of “what if” infectious disease scenarios that healthcare professionals confront routinely. So many questions can and do arise when it comes to the safety and health of your patients, yourself…and even your family! Are your confident in your responses…

  • One patient with an ileal conduit urinary system that, when cultured, revealed microorganisms. Should the treatment include antibiotics…or not?
  • A co-worker is pregnant…which patient rooms won’t pose a potential risk?
  • What innovative skills can you personally incorporate to reduce the incidence of healthcare-associated infections?
  • How can compromised patients be kept safe when multi-drug resistant microorganisms are so prevalent?
  • You’ve been providing great patient care all shift. Now it’s time to head home. How do you make that transition and not introduce your family to some of the infectious diseases you’ve been around?
  • A disease that may be in a distant part of the world could find its way to our backyard! These emerging cases are often complicated in practice. Are you up-to-date to intervene effectively?

Program Information

Objectives

  1. Plan strategies to reduce and eliminate catheter-associated urinary tract infections, surgical site infections, ventilator associated and non-ventilator-associated pneumonias and central-line-associated bloodstream infections.
  2. Assess best practices for treatment and control of multi-drug resistant microorganisms, including MRSA, Clostridium difficile, VRE, ESBL and CRE.
  3. Evaluate the newest vaccine recommendations for healthcare workers and children.
  4. Distinguish between mosquito-borne illnesses of Dengue, Chikungunya, and Zika, which may be a threat to the United States.
  5. Assess the latest treatments available for HIV/AIDS, as well as pre-exposure prophylaxis.
  6. Determine the medications available that "cure" Hepatitis C.
  7. Evaluate the current recommendations to control and treat tuberculosis.

Outline

A Summary of Current Recommendations From the CDC, SHEA, IDSA, APIC and the Joint Commission
 

Health-Care Associated Infections: Strategies to Control-Reduce-Eliminate

  • Catheter-Associated Urinary Tract Infections
  • Surgical Site Infections
  • Ventilator-Associated Pneumonias
  • Non-ventilator Associated Infections (overlooked HAI)
  • Central-Line Associated Bloodstream Infections

The Latest Multi-Drug Resistant Microorganism Guidelines

  • Carbapenem-resistant enterobacteriaceae
  • Clostridium difficile
  • Methicillin-resistant staphylococcus aureus
  • Vancomycin resistant enterococcus
  • Acinetobacter baumannii

Influenza

  • Avian vs. swine vs. seasonal influenza
  • H1N1 pandemic results
  • When to treat? When not to treat?
  • Treatment with anti-virals and antibiotics
  • New vaccines for flu

Vaccination Recommendations for Healthcare Personnel

  • Zoster/shingles
  • Pneumoccocal
  • MMR, Tdap, etc.

Emerging Infectious Diseases (Zoonotic)

  • Ebola: What we learned
  • Mosquito-borne ("Zika", Dengue, Chickungunya, West Nile)
  • Tick-borne (Lyme and Babesia)
  • Cryptosporidiosis

Bloodborne Pathogens

  • Hepatitis B
    • Vaccination protocol for healthcare personnel
    • Staff follow-up after significant exposures
    • Treatments for persons chronically infected
    • Outbreaks in healthcare
  • Hepatitis C
    • Treatment "cures" in 12-24 weeks
    • Outbreaks in healthcare-dialysis settings
  • HIV/AIDS
    • New one pill daily treatment
    • Healthcare exposure and appropriate prophylaxis

Tuberculosis

  • Today's best approaches to treatment
  • Skin testing vs. blood test for exposure
  • Follow-up guidelines for healthcare workers conversion testing

Target Audience

  • Nurses
  • Infection Preventionists
  • Nurse Practitioners
  • Clinical Nurse Specialists
  • Nurse Educators

Copyright : 04/25/2019

Critical Coronavirus Updates for the Healthcare Team

For those of us in healthcare, this past year has been very challenging. We were thrust in to treating a virus that we knew little about. At first.

As time has continued, we have become more skillful at treating patients suffering the consequences of COVID-19. At incredible speed and efficiency, we also now have access to two highly effective vaccines to prevent the virus that causes COVID-19. Because of how quickly new research and new findings are being released related to the vaccines and COVID-19 in general, there are plenty of questions that exist. Questions from patients certainly. And questions for those of us on the frontlines as well.

Watch me, Barry Inman, a CDC/Public Health Epidemiologist, for a 4 hour presentation that will tackle what you must know today. I will synthesize the growing body of evidence and guidelines so that you also have a greater confidence and authority. Let’s continue to learn from one another. To be our best. So that we can give our best to the patients we see. There is so much hope on the horizon!

William “Barry” Inman, BA-BS, CIC, and the PESI Healthcare Team

Program Information

Objectives

  1. Analyze what we continue to learn regarding the modes of transmission.
  2. Determine the risk factors that correlate to complications of COVID-19.
  3. Appraise the best treatments for COVID-19 complications.
  4. Differentiate between the vaccines for COVID-19 in detail (mRNA & vector associated).
  5. Respond confidently to patient questions regarding safety of the COVID-19 vaccines.

Outline

Risk Factors for COVID-19 and Influenza

  • Contact with known case of COVID-19
  • Real risks for healthcare workers
  • Do not come to work ill-no excuse!!
  • 65 years of age or older
  • Co-morbidities
  • Re-admission rates: What is going wrong?
  • The overlap with our typical influenza season
Testing for COVID and Influenza
  • Antigen vs PCR
  • Antibody testing
Critical Infection Control Standards – Keep Your Patients, Yourself and Your Family Safe
  • Influenza –like precautions
  • Disinfecting and isolation
  • Personnel protective equipment – Use and re-use guidelines
Travel
  • Travel time may be extended
  • Is it safe to travel?
  • Precautions
  • Testing before air travel
  • Vaccine
  • Cruise ships-when or if?
Disinfections
  • Does the environment play a major role in transmission?
  • Lipid vs nonlipid microorganisms
  • Appropriate disinfectants
Transmission of COVID-19
  • Days vs. weeks
  • Asymptomatic and pre-symptomatic
  • Antibody testing and immunity
  • Reinfection possibilities
Prevention from Infection for Healthcare Workers
  • Social distancing at work
  • Lunch and social distancing
  • DON and Duff PPEs
  • Masks: N-95 vs. Surgical
  • Handwashing
  • Keep hands from face
  • Being well vaccinated-not just COVID vaccine!
Possible COVID-19 Treatment and Vaccines
  • Remdesvir
  • Lopinavir/Ritonavir
  • Casirivimab and Imdevimab
  • Antibody infusion – Bamlanivimab
Treatments for Influenza and Vaccines
  • Oseltamivir
  • Zanamivir
  • Baloxavir
  • Peramivir
  • Egg based vs recombinant or cell culture vaccine
Vaccine Influenza COVID-19
  • Associated vector and mRNA types
  • Other vaccines platforms
  • Side effects
Strategies to Overcome Vaccine Hesitancy
  • Science vs fiction
  • Be truthful about possible side effects
  • Herd immunity
  • I’ve had COVID-19, should I get the vaccine?
  • Will the COVID-19 vaccine be needed annually

Target Audience

  • Nurse
  • Nurse Practitioners
  • Physician Assistants

Copyright : 04/09/2021